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Year : 2017  |  Volume : 5  |  Issue : 1  |  Page : 1-2

Preface to first issue of Heart India 2017

Department of Cardiology, Heritage Hospital, Varanasi, Uttar Pradesh, India

Date of Web Publication8-Mar-2017

Correspondence Address:
Dr. Alok Kumar Singh
Department of Cardiology, Heritage Hospital, Varanasi - 221 005, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2321-449x.201737

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How to cite this article:
Singh AK. Preface to first issue of Heart India 2017. Heart India 2017;5:1-2

How to cite this URL:
Singh AK. Preface to first issue of Heart India 2017. Heart India [serial online] 2017 [cited 2023 Feb 2];5:1-2. Available from: https://www.heartindia.net/text.asp?2017/5/1/1/201737

In this issue of “Heart India,” we are publishing six original research articles, five case reports and one book review. Subclinical hypothyroidism (SH) is an asymptomatic state and is characterized by elevated levels of thyroid-stimulating hormone and normal free thyroxin (T4) levels.[1] Studies have shown that coronary atherosclerosis in subjects with hypothyroidism is more frequent and severe. In the first original research article, they assessed the relationship between SH and angiographic coronary artery disease. Although the study was small, the result has shown no correlation between SH and angiographic pattern of coronary artery disease. In the second original research article, Shalini et al. have studied the association of Vitamin D and essential hypertension (HTN) in a North Indian population cohort. Authors of this study have concluded that Vitamin D deficiency is more prevalent with HTN, and low levels tend to correlate with elevated systolic blood pressure. However, larger studies are needed to confirm this association.

In the third original research article, Ibrahim et al. have studied the pattern and predictors of outcomes for infective endocarditis in North Kuala Lumpur. A total of 50 patients, 37 (74%) males and 13 (26%) females were included in the study. The mean age was 42 ± 16.4. Most patients (80.39%) were diagnosed within the 1st week of admission. Staphylococcus aureus was the most common pathogen (38%) and the mitral valve was predominantly affected (68%). Complication was common and inhospital mortality remains high (28%). Nearly 20% of the patients who had surgical intervention survived and discharged alive. In the fourth original research article, Sharma et al. have compared the midterm outcomes of mechanical versus bioprosthetic valve replacement in middle-aged patients in India. The overall 10-year survival was similar in patients receiving bioprosthetic heart valve and mechanical heart valves. The incidence of major bleeding episodes was very high with mechanical valves (mitral valve replacement [MVR] = 14.3% and aortic valve replacement [AVR] = 7.2%) as compared to 0.6% and 0.8% with bioprosthetic MVR and AVR, respectively. About 1.02% of patients with tissue valves have episodes of thromboembolism versus 8.3% patients with mechanical valves. Acute valve thrombosis rates were high in mechanical valve (3.1% vs. 0.0%). Incidences of endocarditis were also more with mechanical valve replacement group (2.3% vs. 0.3%). The quality of life was also better in patients with bioprosthetic valves.

In the fifth original research article, Lingeswaran et al. have studied the association between severe periodontitis and carotid intima-media thickness in young adults. Authors of this study have concluded that severe generalized periodontitis is associated with subclinical atherosclerosis in young systemically healthy patients. In the sixth original research article by Peter et al. from Nigeria, they have studied electrocardiographic characteristics of Nigerian children on anthracycline-based chemotherapy. Seventeen children on anthracycline-based regimen for various malignancies in the Paediatric oncology ward of Aminu Kano Teaching Hospital Kano, Nigeria, were recruited for this cross-sectional study. The corrected QT was prolonged in 23.5% of the subjects; the QTc dispersion ranged from 20 to 126 for chest leads and 20–200 for limb leads. Whereas elevation of ST segment occurred in only one patient accounting for 5.9%, ST segment elevation, ST segment depression was present in 6 patients. As per the result of this study, authors of this study have concluded there are remarkable differences in the electrocardiogram (ECG) characteristics of patients in this report who had anthracyclines when compared to apparently healthy children.

In the first case report, Saha et al. have reported two case reports of retrieval of peripherally inserted central catheter from pulmonary artery and dislodged stent from arteria profunda femoris using improvised snares. In the second case report, Sulaiman has reported a case of hyperacute fatal intracerebral hemorrhage following carotid stenting. In the third case report, Osama et al. have reported a case of ventricular septal rupture, right ventricular free wall rupture, hemopericardium, cardiac tamponade, cardiogenic shock, and death in a patient with acute ST elevation myocardial infarction during transthoracic echocardiography. In the fourth case report, Ramnarayan et al. reported a case of a rare presentation of spontaneous ventricular tachycardia in young adult because of arrhythmogenic right ventricular dysplasia. In the fifth case report, Goyal et al. have reported a case of 62-year-old male who presented without an obvious ST elevation in ECG and subsequently found to be having acute obstruction of mid-left anterior descending (LAD) artery. The de Winter pattern on ECG was first recognized and reported by de Winter et al.[2] in 2008. Authors have emphasized the importance of this sign in diagnosing LAD occlusion in acute coronary syndrome.

  References Top

Ross DS. Serum thyroid-stimulating hormone measurement for assessment of thyroid function and disease. Endocrinol Metab Clin North Am 2001;30:245-64, vii.  Back to cited text no. 1
de Winter RJ, Verouden NJ, Wellens HJ, Wilde AA; Interventional Cardiology Group of the Academic Medical Center. A new ECG sign of proximal LAD occlusion. N Engl J Med 2008;359:2071-3.  Back to cited text no. 2


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