Heart India

: 2014  |  Volume : 2  |  Issue : 1  |  Page : 1--2

Preface to first issue of Heart India 2014

Alok Kumar Singh 
 Department of Cardiology, Heritage Hospital, Varanasi, Uttar Pradesh, India

Correspondence Address:
Alok Kumar Singh
Department of Cardiology, Heritage Hospital, Varanasi - 221 005, Uttar Pradesh

How to cite this article:
Singh AK. Preface to first issue of Heart India 2014.Heart India 2014;2:1-2

How to cite this URL:
Singh AK. Preface to first issue of Heart India 2014. Heart India [serial online] 2014 [cited 2022 Sep 29 ];2:1-2
Available from: https://www.heartindia.net/text.asp?2014/2/1/1/127972

Full Text

Heart India is entering into second calendar year after timely publication of three issues in Volume 1, for this grand success I would like to congratulate all our editorial board member, reviewers and authors due to their efforts this journey was very smooth.

Activation of the sympathetic nervous system is an important etiological factor in the pathogenesis of hypertension (HTN) and renal sympathetic nervous system is one of its pivotal arms. Thus, renal sympathetic system was the target of therapy for HTN in the initial period, in the form of sympathectomy. The major adverse events associated with this procedure and the emergence of potent blood pressure (BP) lowering medications led to disrepute of this procedure. Of late, novel techniques targeting the sympathetic nervous system have emerged. Among them and the most promising one is catheter-based radiofrequency ablation of renal nerves - renal sympathetic denervation (RDN). Clinical trials of renal denervation therapy have shown consistent and durable reduction of systolic as well as diastolic BP persisting up to 3 years. Beyond BP control, renal denervation also exerts favorable effects on glucose metabolism, heart failure and sleep apnea. As many as five different catheter-based renal denervation systems are now approved for treating resistant HTN, the maximum clinical experience being with Medtronic's symplicity system. The European Society of Cardiology Guidelines [1] for HTN 2013 now recommends catheter-based renal denervation for management of drug-resistant HTN. In this review, Ameta et al., briefly discuss the role of sympathetic nervous system in the pathogenesis of HTN, the present status and future perspectives of reflex sympathetic dystrophy in the treatment of resistant HTN. It is important to note negative results of SIMPLICITY HTN-3 have lowered down the hypes of RDN.

Acute coronary syndrome is a potentially life-threatening condition and the patient may die or become disabled in the prime of life. In first original research article by Srinivasa et al., have compared risk factor profile for coronary artery disease (CAD) among young and elderly patients in Andhra Pradesh. In this study, young patients had a different risk factor profile when compared with older patients. HTN and smoking were the most common risk factors in young patients of CAD, whereas diabetes mellitus, kidney disease and smoking were found in elderly patients.

The yogic visual concentration technique, trataka is similar to meditation. Research studies have shown a shift toward the vagal tone during meditation. However, autonomic changes in trataka were not studied. In second research article by Raghavendra et al., have assessed the changes in heart rate variability following trataka. The present study have shown that practice of trataka leads to increased vagal tone and reduced sympathetic arousal. Though trataka is known as cleansing technique, it could induce calm state of mind, which is similar to a mental state reached by the practice of meditation.

In the first case report by Ibrahim from Nigeria have reported a rare case of cor triloculares biatritum, which is a rare congenital heart disease characterized by a three-chambered heart consisting of two atria and a single ventricle; however, the case of a 5-month-old African boy who in addition to this defect had an associated tricuspid atresia and an atrial septal defect of sinus venosus type.

Rasopathy syndromes are a class of phenotypically similar, but genetically distinct multiple anomaly syndromes caused by germ line mutations in genes that encode protein components of the Ras/mitogen activated protein kinase pathway. Noonan syndrome, cardiofaciocutaneous syndrome and Costello syndrome are part of this group of developmental syndromes and have similar cardiac abnormalities. In the second case report by Kadiyala et al., have reported bilateral branch pulmonary artery stenosis and mitral valve prolapse in a patient with Noonan syndrome. Dilated cardiomyopathy (DCM) commonly presents with exertional dyspnea, fatigue, dependent edema and ascites. Jugular venous distension with prominent positive waves, S3 gallop and regurgitant murmur are usual signs of DCM. In the last case report of this issue by Mondal et al., have reported case of DCM presenting like a superior vena cava syndrome.


1Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Böhm M, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2013;34:2159-219.